Isatoic Anhydride MSDS Sheet

Aadhunik Industries is a manufacturing group company. Aadhunik Industries is pioneer manufacturers of Isatoic Anhydride, Specialty Chemicals, Pharmaceutical Excipients, Food Fragrance & Flavor chemicals in India. It has toll manufacturers and representatives in UAE, Europe, Canada & USA and agents & customers in all countries like USA, Canada, Europe, UAE, South Africa, Tanzania, Kenya, Egypt, Nigeria, Uganda, Turkey, Mexico, Brazil, Chile, Argentina, Dubai, Netherlands, Italy, Spain, Germany, Portugal, France, Malaysia, Indonesia, Thailand, Korea, Japan, Russia etc.

Aadhunik Industries and/or associated units are FDA-GMP certified, Halal and/or Kosher certified, REACH registered, ISO-9001, ISO-22000 HACCP certified. We offer crystals granules in precise micron or mesh size as per buyers needs. We offer very high purity standards as per specifications required.

Synonyms: 4H-3,1-benzoxazine-2,4(1H)-dione; 1,2-Dihydro-4H-3,1-benzoxazine-2,4-dione; 2H-3,1-Benzoxazine-2,4(1H)-dione; Anthranilic Acid, N-carboxy-, Cyclic Anhydride; Isatoic Acid Anhydride; Benzoic Acid, 2-(Carboxyamino)-, Cyclic Anhydride; N-carboxyanthranilic Anhydride; 4H-3,1-benzoxazina-2,4(1H)-diona (Spanish); Anthranilic acid N-carboxylic acid anhydride.
CAS No.: 118-48-9
EINECS: EC Number: 204-255-0
Molecular Weight: 163.13
Chemical Formula: C8H5NO3

Ingredient: Isatoic Anhydride
CAS No.: 118-48-9
Percent: 97 - 100%
Hazardous: Yes

Emergency Overview
Warning! Causes eye and skin irritation. Causes digestive and respiratory tract irritation. Moisture sensitive. The toxicological properties of this material have not been fully investigated.
Target Organs: None.

OSHA Hazards: Skin sensitizer, Irritant.
HMIS Classification
Health hazard: 2
Flammability: 1
Physical hazards: 0
NFPA Rating
Health hazard: 2
Fire: 1
Reactivity Hazard: 0

Potential Health Effects
Inhalation: Harmful. It may cause irritation to the respiratory tract.
Ingestion: Harmful if swallowed. It can irritate the digestive system.
Skin Contact: Harmful. It may cause irritation with redness and pain.
Eye Contact: Isatoic Anhydride contact may cause irritation, redness, and pain.
Chronic Exposure: No information found for Isatoic Anhydride.
Aggravation of Pre-existing Conditions: Persons with pre-existing skin disorders or eye problems or impaired respiratory function may be more susceptible to the effects of the substance.
Carcinogenic Effects: Not a reported carcinogen.
Mutagenic Effects: Not available. It may have mutagenic effect.
Teratogenic Effects: Not available.
Developmental Toxicity: Not available.

Inhalation: Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention.
Ingestion: Never give anything by mouth to an unconscious person. Get medical attention.
Skin Contact: Wipe off excess material from skin then immediately flush skin with plenty of water for at least 15 minutes. Remove contaminated clothing and shoes. Get medical attention. Wash clothing before reuse. Thoroughly clean shoes before reuse.
Eye Contact: Immediately flush eyes with plenty of water for at least 15 minutes, lifting lower and upper eyelids occasionally. Get medical attention immediately.
Note to Physician: Treat symptomatically.

Flammability of the Product: The product is flammable.
Auto-Ignition Temperature: 350.
Flash Points: 308C.
Products of Combustion: It forms oxides of carbon nitrogen and toxic gases when heated to decomposition. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas.
Explosion: Not known.
Fire Extinguishing Media: Use water spray, dry chemical, foam, or carbon dioxide.
Special Information In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures or when moistened under fire conditions, it may produce toxic or irritating fumes.

Small Spill: Avoid dust formation. Avoid breathing dust. Ensure adequate ventilation. Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and dispose of according to local and regional authority requirements.
Large Spill: Do not let the product enter drains. Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water and swab.

Do not breathe dust. Wear suitable protective clothing. In case of insufficient ventilation, wear suitable respiratory equipment.
Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Wash hands thoroughly after handling. Provide appropriate exhaust ventilation at places where dust is formed. If you feel unwell, seek medical attention.
Keep Isatoic Anhydride in a tightly closed container, stored in a cool, dry, ventilated area. Protect against physical damage or contact with oxidizing material and combustible substances. Avoid moisture and store away from water sources.

Airborne Exposure Limits: None established.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator may be worn. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Dust deposits on floors and other surfaces may pick up moisture and cause the surfaces to become slippery and present safety hazards. Handle in accordance with good industrial hygiene and safety practice. Wash hands after handling.

Appearance: Isatoic Anhydride is tan coloured crystals or powder.
Odor: Typical
Solubility: Readily soluble in water.
pH: 5.6
Molecular Weight: 163.13
Molecular Formula: C8H5NO3
% Volatiles by volume @ 21C (70F): 0
Boiling Point: NA
Melting Point: 235-237 C Decomposes
Vapor Density (Air=1): No information found
Vapor Pressure (mm Hg): No information found
Evaporation Rate (BuAc=1): No information found

Stability: Isatoic Anhydride is stable under recommended conditions of use and storage.
Hazardous Decomposition Products: It produces oxides of carbon nitrogen along with toxic fumes when heated to decomposition.
Hazardous Polymerization: Will not occur.
Incompatibilities: Isatoic Anhydride is incompatible with water including moisture, heat, oxidizing material, strong acids & alkalis.
Conditions to Avoid: Moisture, Heat, Sun light, Incompatibles.

Routes of Entry: Inhalation, Ingestion, Contact.
RTECS: CAS# 118-48-9: DM3100000
Toxicity to Animals:
Oral, mouse: LD50 = NA
Oral, rat: LD50 = NA
Special Remarks on Toxicity to Animals: Not available.
Carcinogenic Effects: Not a reported carcinogen.
Mutagenic Effects: Not available.
Teratogenic Effects: Not available.
Developmental Toxicity: Not available.
Chronic Effects on Humans: It may be mutagenic though no studies are found.
Other Toxic Effects on Humans: Hazardous in case of skin contact, of ingestion, of inhalation.
Special Remarks on Chronic Effects on Humans: -
Special Remarks on other Toxic Effects on Humans: -
Acute Potential Health Effects:
Inhalation: Isatoic Anhydride causes irritation to the respiratory tract and mucus membrane.
Ingestion: Harmful if swallowed. May cause irritation and disorder of the gastrointestinal tract.
Skin Contact: Isatoic Anhydride causes irritation to skin.
Eye Contact: Causes irritation redness pain and burning of eyes.
Chronic Exposure: NA.

Environmental Toxicity:
Toxicity to fish:
No data found
Toxicity to daphnia and other aquatic invertebrates:
No data found
Biodegradability: -
BOD5 and COD: Not available.
Environmental Fate: No information found.

Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste disposal facility. Processing, use or contamination of this product may change the waste management options. State and local disposal regulations may differ from federal disposal regulations. Dispose of container and unused Isatoic Anhydride in accordance with federal, state and local requirements.

OSHA Hazards: Skin Sensitizer, Irritant.
SARA 302: No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302.
Section 313: No chemicals are reportable under Section 313.
SARA 311/312 Hazards: Acute Health Hazard.
TSCA: CAS# 118-48-9 is on the TSCA Inventory.
CERCLA Hazardous Substances and corresponding RQs: -.
Health & Safety Reporting List: None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules: None of the chemicals in this product are under a Chemical Test Rule.
Section 12b: None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule: None of the chemicals in this material have a SNUR under TSCA.

California Prop 65:
Not listed.
Massachusetts Right To Know Components:
Not listed.
Pennsylvania Right To Know Components:
4H-3,1-Benzoxazine-2,4(1H)-dione
CAS-No.: 118-48-9
New Jersey Right To Know Components:
4H-3,1-Benzoxazine-2,4(1H)-dione
CAS-No.: 118-48-9
Clean Air Act:
This material does not contain any hazardous air pollutants.
This material does not contain any Class 1 Ozone depletors.
This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
None of the chemicals in this product are listed as Hazardous Substances under the CWA.
None of the chemicals in this product are listed as Priority Pollutants under the CWA.
None of the chemicals in this product are listed as Toxic Pollutants under the CWA.

EINECS: EC Number: 204-255-0
European Labeling in Accordance with EC Directives
Hazard Symbols:
XI
Risk Phrases:
R 36/37/38 Irritating to eyes, respiratory system and skin.
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
S 37 Wear suitable gloves.
S 45 In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
S 28A After contact with skin, wash immediately with plenty of water.
WGK (Water Danger/Protection)
CAS# 118-48-9: 1

Canada - DSL/NDSL
This product contains the following components listed on the Canadian NDSL list. All other components are on the
Canadian DSL list.
4H-3,1-Benzoxazine-2,4(1H)-dione
CAS-No.: 118-48-9
Canada - WHMIS
CAS# 118-48-9 is not listed on Canada's Ingredient Disclosure List.

Disclaimer:
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Our company provides this Isatoic Anhydride MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This Isatoic Anhydride MSDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.
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CAS Number 118-48-9, Isatoic Anhydride manufacturers suppliers exporters at:

manufacturer supplier exporter
Aadhunik Industries
Ankleshwar Gujarat & Mumbai, India
TEL: (OFFICE) 91-22-23774610, 23723564.